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In the SELECT CV outcome trial, which included patients aged 45 years or older with a body mass index (BMI) 27.0 kg m 2 and established ASCVD but without diabetes, those treated with the glucagon-like peptide-1 receptor agonist (GLP-1RA), semaglutide 2.4 mg, had a 20% MACE reduction compared with those receiving placebo on top of standard of care 12

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Its Too Expensive : Lets face it, GLP-1 medications like Zepbound and Wegovy are pricey, and insurance companies dont want to pay for it