Miglustat is currently the only causal treatment for neurological manifestations (Patterson et al., 2020)
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This delivery method is said to improve absorption and enhance effectiveness
The most reproducible single mechanism is non-canonical activation of the VEGFR2-Akt-eNOS axis : Hsieh and colleagues showed that BPC-157 induces VEGFR2 internalization and downstream signaling in endothelial cells in the absence of VEGF, supporting capillary outgrowth in the wound bed