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As this can be an unreliable indication of cellular B12 levels, it is recommended to consider holotranscobalamin, homocysteine, methylmalonic acid and/or genetic testing in conjunction with this, in order to create a more accurate picture of B12 status

Without adequate circulation, the injured tissue cannot receive the oxygen and nutrients necessary for repair, nor can it efficiently remove metabolic waste products

A standard treatment plan starts with 0.25mg per week

However, available human studies indicate that NAD + is rapidly cleared from the plasma for at least the first two hours of infusion, reflecting immediate tissue uptake and/or metabolism