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In addition to their weight loss benefits, these drugs also act through gut-brain signaling and central nervous system pathways involved in appetite, reward, and feeding behavior, although the extent to which individual agents cross the blood-brain barrier remains an active area of investigation

GLP-1s can be used in people with type 2 diabetes to help regulate blood glucose

148 The dark side hypothesis of addiction suggests that impulsivity, compulsivity, and negative urgency emerge from stress experienced during withdrawal or the negative affective phase, potentially persisting months post-withdrawal

Plastic containers can release chemicals when heated repeatedly, potentially contributing to digestive discomfort