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However, they should not yet be interpreted as evidence of a direct therapeutic effect on depression or anxiety. The research came as a separate study found that women taking semaglutide for diabetes before they knew they were pregnant had a 84% higher relative risk of preterm birth, compared with those who did not take GLP-1 medication, while the risk was 70% higher with liraglutide

"Many of us from underrepresented groups pursue medicine to advocate for equitable healthcare for those with similar experiences, said Dr

SURPASS-CVOT is unique, in that it compares the dual incretin agonist with a GLP-1 RA that has been shown to have cardiovascular benefit in people with type 2 diabetes and high risk ASCVD

Key takeaways Semaglutide and testosterone replacement therapy (TRT) are generally considered safe to take together and may work well in combination, but only for men with clinically confirmed low testosterone