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Description

Impaired adipose NAMPT-NAD+-SIRT1-PPAR axis contributes to the development of obesity and its metabolic complications and thus it could be a promising therapeutic target for obesity treatment

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Patients were additionally required to have 1 of the following based on data from the 1-year baseline period or the index date: 1 International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code or electronic medical record indicating overweight (BMI of 2529.9 kg/m) with 1 obesity-related complication (identified through ICD-10 diagnosis codes) or 1 ICD-10 diagnosis code or electronic medical record indicating obesity (BMI 30 kg/m 2

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