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If all three phases of the two-sample MR analyses indicated significant causal associations, mediation was considered to be established and the mediation proportion in addition to its strengths were subsequently calculated

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Taking appropriate steps in the retail environment includes requiring tobacco products to be located behind the counter, posting signage informing customers that it is illegal for minors to purchase tobacco, and banning vending machines and self-service sales (Forster and Wolfson 1998)

New models appear regularly, often shortly after they are released to the market